منابع مشابه
Recent advances in cancer immunotherapy
Laboratory and clinical investigations of immunotherapy in cancer treatment have been underway for the past several decades by attempting to stimulate, enhance, and modulate the immune system to detect and destroy cancer cells. Although immunotherapy has shown success in a wide variety of cancers previously: BCG in superficial bladder cancer, interferon-alpha in melanoma, and high-dose interleu...
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In recent years, the introduction and Federal Drug Administration approval of immune checkpoint inhibitor antibodies has dramatically improved the clinical outcomes for patients with advanced melanoma. These antagonist monoclonal antibodies are capable of unleashing dormant or exhausted antitumor immunity, which has led to durable complete and partial responses in a large number of patients. Ip...
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Adoptive immunotherapy is an attractive and elegant strategy for treating a variety of life-threatening diseases. Several approaches have been developed to generate antigen-specific CD4+ and CD8+ T cells for adoptive T-cell therapy in cancer and infectious diseases. Currently, many approaches are based on either the use of autologous peptide pulsed dendritic cells as antigen-presenting cells or...
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Pancreatic cancer is one of the more difficult malignancies to treat, and there is a great need for less toxic, effective regimens. Immunotherapy has shown potential in the treatment of pancreatic cancer, and at ASCO 2013 there were several progressive advances in its clinical application. Abstracts #3067, #3049, #3007, #4040, #LBA4004, and #3090 will be discussed. New developments in the field...
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Immunotherapy is heralded as one of the most important advances in oncology. Until recently, only limited immunotherapeutic options were available in selected immunogenic cancers like melanoma and renal cell carcinomas. Nowadays, there is an improved understanding that anti-tumor immunity is controlled by a delicate balance in the tumor microenvironment between immune stimulatory and immune inh...
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ژورنال
عنوان ژورنال: Immunotherapy Advances
سال: 2020
ISSN: 2732-4303
DOI: 10.1093/immadv/ltaa009